By David Steensma
Written via a crew of top professionals in pathogenesis, diagnostic suggestions, and scientific administration techniques in myelodysplastic syndrome (MDS), this article presents a concise, easy-to-follow overview of the advances within the technological know-how, type, analysis, and administration of the .
An perfect resource for hematologists, oncologists, and melanoma researchers, this Second Edition features:
- a new eight-page colour insert
- 200 colour and black-and-white illustrations
- reworked content material equipped into 3 sections: MDS epidemiology and biology; analysis, class, and analysis; and MDS therapy
- thoroughly up to date chapters reflecting a shift from the topical concentration as dictated by means of the evolution of the field
New themes in Myelodysplastic Syndrome include:
- del(5q) and 5q-syndrome, CMML, and MDS-MPD overlap syndrome
- the reborn DNA methyltransferase inhibiting nucleoside analogs
- the prognosis of persistent myelomonocytic leukemia and different MDS circumstances with myeloproliferative features
- the position of mitochondria and the capability significance of iron overload in MDS
- global genomics techniques, similar to cDNA expression arrays, array-based comparative genomic hybridization, and unmarried nucleotide polymorphism array
- the function of irregular mitochondrial ferritin accumulation and different mitochondrial metabolic anomalies in MD
- other disease-associated adjustments, similar to abnormalities of B lymphocyte populations in MD
- three lately licensed medications: azacitidine, lenalidomide, and decitabine
Read Online or Download Myelodysplastic Syndromes: Pathobiology and Clinical Management (Basic and Clinical Oncology) PDF
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Myelodysplastic Syndromes: Pathobiology and Clinical Management (Basic and Clinical Oncology) by David Steensma